Photodynamic Therapy to Treat Actinic Damage in Patients With Squamous Cell Carcinoma (SCC) of the Lip

Inclusion Criteria: * Biopsy proven squamous cell carcinoma of the lip * Greater than 50% of lip affected by actinic cheilitis by physical exam at time of initial evaluation. * Patients \> 18 years of age * Patients must be able to provide informed consent Exclusion Criteria: * Patients with history of photosensitivity * Patients with medical conditions associated with photosensitivity, such as cutaneous porphyria or a collagen vascular disease * Patients taking medications known to cause photosensitivity (tetracyclines, sulfonamides, phenothiazines, sulfonylurea hypoglycemic agents, thiazide diuretics, griseofulvin, and fluoroquinolones) * Patients with hypersensitivity to porphyrins. * Women who are pregnant or nursing * No exclusion based on gender or race * Patients who have received anti-neoplastic treatment such as imiquimod or 5-FU to the lips within 30 days of enrolling in this study. * Patients simultaneously participating in another research study for management of SCC or actinic cheilitis * Subjects that plan to use other forms of AC treatment prior to Mohs. * Subjects that have an SCC requiring urgent (and sooner) Mohs surgery, including those tumors that are large (\> 2cm or at the discretion of the Principle Investigator) and those subjects that are pregnant or have palpable lymph nodes.