Real Time Myocardial Contrast Echocardiography and Dobutamine Stress Perfusion Magnetic Resonance Imaging

Inclusion Criteria:• Age between 12 years and 50 years. * Male or female. * History of repaired congenital heart disease including atrial septal defects, aortic valve disease, tetralogy of fallot, transposition of great arteries and anomalous left coronary artery from pulmonary artery. * History of sequelae of heart disease acquired as an infant or child, including Kawasaki disease and coronary ectasia, and patients post anthracycline chemotherapy. * Ability to perform Supine bicycle stress with contrast echocardiography as determined by primary cardiologist and/or Dr. Shelby Kutty. * Ability to perform CMR with dobutamine stress as determined by the patients primary cardiologist and/or Dr. Shelby Kutty * Signed informed consent and assent as applicable. Exclusion Criteria:• Atrial or ventricular arrythmias that cannot be controlled to heart rates \< 70/min * Intracardiac shunts * Known hypersensitivity to perflutren * Known hypersensitivity to Dobutamine * Congestive heart failure in NYHA class II, III or IV * Claustrophobia or any other reason patient is unable to perform CMR (i.e. ferromagnetic implants causing significant artifact that alters image quality, presence of pacemaker, AICD, etc.) * Pregnant or possibly pregnant (based on history/information obtained from the patient) or breast feeding