UnknownNot Applicable

Characterization of Receptors in Non-functioning Pituitary Macroadenomas

United States100 participantsStarted 2006-03

Plain-language summary

Characterization of receptors present in non-functioning pituitary macroadenomas by Reverse Transcriptase- Polymerase Chain Reaction (RT-PCR) would assist with targeted medical therapy based on the information obtained by immunohistochemistry and RT-PCR.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Adults, both males and females age 18 years old or more
✓. Pituitary tumor more than 10 mm in diameter diagnosed by MRI
✓. No clinical or laboratory evidence of pituitary hormone oversecretion (non-functioning pituitary macroadenoma)

Exclusion criteria

✕. Subjects with pituitary tumors less than 10 mm in diameter
✕. Subjects with clinical or laboratory evidence of hormone oversecretion
✕. Presence of dementia

What they're measuring

To determine the expression of hormonal receptors in clinically non-functioning pituitary macroadenomas by RT - PCR and immunohistochemistry.

Timeframe: 2 years

Trial details

NCT IDNCT00852501

SponsorCook County Health

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2013-12

Contact for this trial

Ambika Babu, MD

312 864 0543 Ambika_Babu@rush.edu

View on ClinicalTrials.gov More Pituitary Tumor trials