Feasibility Study of Prostate Tumor Localization for Focal Cryoablation of Prostate Carcinoma (NCT00851682) | Clinical Trial Compass
TerminatedNot Applicable
Feasibility Study of Prostate Tumor Localization for Focal Cryoablation of Prostate Carcinoma
Stopped: Enrollment was stopped and will not resume. Participants are no longer being examined.
United States65 participantsStarted 2009-01
Plain-language summary
The purpose of the present study is to find out if MRI techniques examining (1) the motion of water molecules in the prostate (diffusion sensitive MRI), (2) the difference in blood flow to the prostate (dynamic contrast enhanced MRI), and (3) differences in chemical composition of the prostate (MR spectroscopy), can be used to detect prostate cancer early and non-invasively. Localization of the cancer within the prostate would be of particular importance in focal cryoablation of prostate carcinoma which we hope to improve as a result of this project.
Additional aim of the study is to correlate expression of genes believed to pay a role in prostate cancer with MRI findings.
Who can participate
Age range
20 Years – 85 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patients who have been diagnosed with prostate cancer and are scheduled for radical prostatectomy or for brachytherapy
* patients who have not received any preoperative treatment for their diagnosis of prostate cancer
Exclusion Criteria:
* patients with implants that are electronically, magnetically, or mechanically active
* patients with intracranial aneurysm clips
* patients who have undergone cosmetic eyelid surgery
* patients with history of pheochromocytoma, insulinoma and acute glaucoma
* patients with estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m2
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Improved Accuracy of Prostate Cancer Detection by MRI Scan.