Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury

Inclusion Criteria: * Subject has had a brain injury at least 12 months prior to study enrollment. * Subject is at least 18 years old. * Etiology of brain injury: Stroke, anoxia, and trauma * Must be able to equalize ears, or have tympanostomy tubes * Willingness to complete outcome measures and complies with the research protocols. * Commitment to pay the hospital for hyperbaric oxygen. Exclusion Criteria: * Glasgow Coma Scores less than 13 at the time of hyperbaric oxygen evaluation. * Poorly controlled seizures(ie:\>1 generalized seizure in past 3 months despite appropriate anticonvulsant therapy). Pharmacologically-controlled seizures or focal seizures are not an exclusion to participate. * Inability to participate in outcome assessments (eg: blindness, quadraplegia) * Claustrophobia (unwillingness or inability to enter the hyperbaric chamber). * Inability to equalize ears. The patient could elect to have bilateral tympanostomy tubes. * Inability to protect airway, and or requiring frequent suctioning. * Patients requiring tracheostomy will be ineligible due to limitations in autoinflation of the middle ear space and difficulty to perform airway suctioning in the single-person chamber. * Pregnancy (beta HCG will be assayed in women who could be pregnant prior to enrollment). * Severe psychiatric disorders such as schizophrenia and bi-polar disease. We appreciate that psychiatric problems such as depression and anxiety may follow brain injuries so we would not exclude p…