CompletedNot Applicable

Alveolar Macrophage Proteomics in HIV-associated Emphysema

United States365 participantsStarted 2006-04-21

Plain-language summary

This study is being done to examine lung function changes in individuals with HIV infection and to understand why individuals with HIV have increased risk of lung damage from cigarette smoking.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clinically stable HIV-seropositive (and HIV-seronegative) individuals * Ages 18 years and older * Female subjects on no oral contraception with a negative pregnancy test * Subjects capable of giving written consent Exclusion Criteria: * Known medical illness that would preclude bronchoscopy/BAL (e.g. unstable angina, new cardiac arrhythmia). This only pertains to subjects involved in the bronchoscopy phase of the study. * Pregnant females * Prisoners

What they're measuring

examine the natural history of smoking related lung damage in patients with HIV

Timeframe: 3 years

Trial details

NCT IDNCT00823927

SponsorPhilip Diaz

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2008-06-23

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