CompletedPhase 2

Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)

United States33 participantsStarted 2008-08

Plain-language summary

The purpose of this study is to perform a randomized double-blind, placebo-controlled, 12 week study of the effects of carnosine on cognitive, psychometric, autonomic, and muscle strength outcomes in 100 GWI subjects.

Who can participate

Age range34 Years – 82 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Evidence of military enlistment between August 1, 1990 and July 31, 1991, and deployment for 30 consecutive days to: * Persian Gulf waters and adjacent land areas, * Other global locations, or, * U.S. only. 1990-1991 enlistment status: * Active duty * National Guard * Reserves Exclusion Criteria: * HIV/AIDS * Pregnant Women * Active Duty Military Personnel * Children * Incarceration

What they're measuring

Effect of Carnosine Supplementation on Chronic Fatigue Syndrome Severity Scores

Timeframe: Weeks 0 and 12

Subjects With Improved Diarrhea Symptoms

Timeframe: Weeks 0 and 12

Incremental Change in Fatigue Score From Baseline to Week 12

Timeframe: Week 0 and Week 12

SF36 Bodily Pain

Timeframe: Week 0 and Week 12

Incremental Change in Generalized Anxiety Scale (GAD) Scores From Baseline to Week 12

Timeframe: Week 0 and Week 12

Incremental Change in SF36 General Health Between Baseline and Week 12

Timeframe: Week 0 and Week 12

Trial details

NCT IDNCT00810368

SponsorGeorgetown University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-07

Results submitted2014-03-24

View on ClinicalTrials.gov More Persian Gulf Syndrome trials