CompletedNot Applicable

Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)

United States92 participantsStarted 2008-05

Plain-language summary

The purpose of this study is to track areas of the brain, via functional magnetic resonance imaging (fMRI), that retain structural and functional integrity throughout the lifespan of people with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Participants with and without ALS must: * be between 18 and 70 years of age * not be claustrophobic * not have metal particles in their eyes * not have metal implants (joints, inner ear, pacemaker, etc.) or foreign metal in their body * not have a history of neurological or psychiatric disorder * not have a history of alcohol or drug abuse * be able to lie on their back for 90 minutes * not be dependent on artificial ventilation * not be on PiPap, or must be capable of being off it for greater than 6 hours * healthy controls must be over the age of 40

What they're measuring

cortical activation patterns

Timeframe: Yearly

Trial details

NCT IDNCT00809224

SponsorUniversity of Michigan

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-05

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