CompletedPhase 1

A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.

United States21 participantsStarted 2008-11

Plain-language summary

The purpose of this study is to improve port wine stain therapeutic outcome in response to laser therapy. The researchers want to determine whether the combined use of pulsed dye laser therapy and rapamycin will improve PWS therapeutic outcome.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * port wine stain birthmarks suitable for comparison testing. Exclusion Criteria: * Pregnancy. * Abnormal blood hematology or chemistry blood tests or urine analysis. * History of cancer, History of high cholesterol, lipids or liver disease * Allergy to macrolide drugs (e.g., erythromycin). * Any therapy within the previous two months to the proposed PWS treatment sites. * Concurrent use of known photosensitizing drugs,immunosuppressive drugs or systemic steroids,antifungals, antiepileptics, HIV protease inhibitors, cimetidine, cisapride, clarithromycin, dannzol, diltiazem, erythromycin, metoclopramide, rifabutin, rifampin, rifapentine, troleandomycin, or verapamil.

What they're measuring

improve port wine stain (PWS) therapeutic outcome

Timeframe: 8 weeks

Trial details

NCT IDNCT00800722

SponsorUniversity of California, Irvine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-06

View on ClinicalTrials.gov More Port Wine Stain trials