UnknownNot Applicable

Specific Inspiratory Muscle Training (SIMT)in the Patients With Ventilatory Dependence

Thailand20 participantsStarted 2007-01

Plain-language summary

Prolong mechanical ventilation cause to respiratory muscle weakness and high risk to weaning failure,the investigators hypothesize that 1. Specific inspiratory muscle training (SIMT) using threshold loaded breathing device (BreatheMAX V.1)in patients with ventilator dependence will improve inspiratory muscle strength 2. SIMT will improve lung function in patients with ventilatory dependence. 3. SIMT will improve weaning success in patients with ventilatory dependence.

Who can participate

Age range30 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient who have been mechanically ventilated \> 72 hours and start to weaning from medical order or ventilator dependent patients who have failed to wean prior to study. * Normal arterial blood gas (PaCO2 \< 50mmHg, PaO2 \> 60 mmHg on FiO2 \<0.5 or SaO2 \> 90%, PH 7.35-7.45). * Cardiovascular stability (HR ≤ 140 beats/min, systolic BP 90-140 mmHg and diastolic BP 60-90 mmHg, with no or minimal vasopressors) * Good consciousness, cooperation and can sit in an upright position \> 30 minutes Exclusion Criteria: * Persistent homodynamic instability. * Severe breathlessness at rest when spontaneous breathing. * Coronary heart disease with angina. * Life threatening arrhythmia (VF, VT). * Sedation Ramsay scale \> 2 * Severity of disease APACHE II score \> 29

What they're measuring

Peak Negative Inspiratory Pressure (PNIP)

Timeframe: every 7 day for 28 days

Trial details

NCT IDNCT00792441

SponsorSaikaew Chuachan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2009-12

View on ClinicalTrials.gov More Ventilatory Defect trials