CompletedNot Applicable

The Role of Serum Anticholinergic Activity in ACVB Patients

Germany100 participantsStarted 2008-05

Plain-language summary

Drugs with anticholinergic potential increase the risk of postoperative transient and persistent cognitive dysfunction especially in cardiac patients. The investigators main goal is to identify preoperative risk factors and to monitor postoperative patients' state in relation to SAA activity and bilateral BIS-EEG changes.

Who can participate

Age range55 Years – 90 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * written compliance to the study participation * a good knowledge in German speech * no red/ green blindness * no previous neurological and/or psychiatric illness * good ability to see and to hear * Mini-Mental-State-Examination (MMSE) better than 25 points Exclusion Criteria: * no written compliance to the study participation * bad knowledge in German speech * red/ green blindness * previous neurological and/or psychiatric illness * no ability to see and to hear * Mini-Mental-State-Examination (MMSE) lower than 25 points

What they're measuring

Cognitive dysfunction measured by neurocognitive test battery

Timeframe: 3 month postsurgery

Trial details

NCT IDNCT00782938

SponsorHeidelberg University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2009-12

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