Probiotics as a Prophylactic Aid in Women With Recurrent Urinary Tract Infections (UTI's) (NCT00781625) | Clinical Trial Compass
UnknownNot Applicable
Probiotics as a Prophylactic Aid in Women With Recurrent Urinary Tract Infections (UTI's)
Norway120 participantsStarted 2008-10
Plain-language summary
To investigate if administration of probiotics, either orally or vaginally,
* Can reduce the number of episodes of acute bacterial cystitis and/or
* Has tolerable adverse effect profile
* Improves general QoL in these women
* Improves the immune function and other physiological stress markers
* Reduces inflammation in urinary bladder epithelium
Who can participate
Age range
18 Years – 70 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* women 18-70 years old
* spontaneous urination
* \> 3 UTI's previous year
* no ongoing prophylactic antibiotic treatment
Exclusion Criteria:
* \> 50 ml residual urine
* neurological bladder disease
* known neoplasia, kidney stone or urinary tract abnormalities
* use og indwelling catheter
* pregnancy
* diabetes
* infrequent voiding pattern
* symptoms that indicate interstitial cystitis
* creatinin \> 250 micmol/L
* participating in other clinical trial
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is looking at probiotics as a way to reduce how often recurrent UTIs come back — given my own history of UTIs, does my doctor think probiotics could realistically help in my specific case, or are there other preventive options that have stronger evidence behind them?
2Since this trial is listed with an 'unknown' recruitment status, is it still actively enrolling patients, and if not, are there similar or more recent studies on probiotics for UTI prevention that my doctor would recommend I look into instead?
3The trial measures improvement in quality of life alongside UTI frequency — what does my doctor think a realistic reduction in UTI episodes would need to look like before switching from a prescription antibiotic prevention plan to something like probiotics?
4Probiotics are generally considered low-risk, but since this trial is Phase NA and I may not have full safety and effectiveness data, what does my doctor know about any side effects or limitations of using probiotics long-term for UTI prevention?
5Would participating in or following a probiotic-based approach like this trial mean pausing or changing my current UTI treatment, and how would my doctor recommend I weigh that trade-off?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.