Subcutaneous Rehydration Compared to Intravenous Rehydration

Inclusion Criteria: * Children of either gender from one month to ≤10 years of age. * Patients with mild or moderate dehydration * Healthy child except for the underlying etiology for dehydration * Pre-dehydration body weight ≥ 5th percentile for age * Parents or legal guardian(s) available to provide informed consent. Exclusion Criteria: * Severe dehydration * Shock or life-threatening situation (life expectancy \< 10 days). * Requirement for IV access for any indication other than for treatment of dehydration. * Indwelling IV catheter, except for one intended only for collection of clinical laboratory specimens. * Any condition precluding SC infusion or infusion site evaluation * Any reason (prior to study enrollment) for a hospital admission or an extended stay in the ED for other than dehydration. * Known hypersensitivity to hyaluronidase or hylenex. * Known hyponatremia (\< 130 milliequivalents per liter \[mEq/L\]) or hypernatremia (\> 155 mEq/L). * Known hypokalemia (\< 3.0 mEq/L). * Any medical condition likely to interfere with the patient's ability to fully complete all protocol-specified interventions, the ability to undergo all protocol-specified assessments, or likely to prolong the patient's need for medical attention beyond that required for treatment of dehydration. * Participation in an investigational drug or device study within 30 days prior to enrollment in this study.