CompletedNot Applicable

Vitamin D Replacement After Kidney Transplant

United States116 participantsStarted 2008-10-01

Plain-language summary

Vitamin D deficiency accelerates vascular risk progression after kidney transplant.

Who can participate

Age range

19 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Kidney transplant more than 6 months ago * 19 years or older * 25-hydroxy vitamin D ≤35 ng/ml Exclusion Criteria: * Estimated Glomerular filtration rate (GFR) \<30 ml/min/1.73m² * Previous small bowel or lung transplant * Pancreas transplant less than 6 months ago * Cancer or any condition that would change their weight dramatically in the near future such as malabsorption * Willing to return for testing every two months * Women who are pregnant or \< 6 weeks postpartum * Calcium \> 10.5 mg/dl * Phosphate \> 4.8 mg/dl * Drinking more than 2 alcohol drinks a day or 14 drinks per week * History of parathyroid surgery * Known granulomatous disease * Taking any seizure medication that affects vitamin D * Taking Zemplar ® and/or Rocaltrol ® * History of kidney stones in the past 20 years * Not on a stable dose of bisphosphonate for the past three months * Planning on a pancreas transplant within the next year * In any other research study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Compare Efficacy and Safety of Two Vitamin D Supplements of These Doses in Normalizing Vitamin D Concentrations.

Timeframe: Baseline and 6 months

Trial details

NCT IDNCT00748618

SponsorUniversity of Nebraska

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-04-01

Results submitted2023-06-19

View on ClinicalTrials.gov More Kidney Transplantation trials

Who can participate

Age range

19 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.