WithdrawnNot Applicable

The Use of L-Carnitine And CoQ10 Supplements In the Treatment of Cyclic Vomiting Syndrome (CVS)

Stopped: No funding

United States0Started 2007-10

Plain-language summary

This is a study with the principle goal being to learn about the use of L-Carnitine and CoQ10, two vitamin supplements that are currently being used to treat Cyclic Vomiting Syndrome, largely initiated by parents. We want to learn how effective these supplements are compared to standard treatment, at what dose, and what onset of action in order to initiate future prospective study on these supplements.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 3 discrete episodes of vomiting * normal health between episodes * stereotypical clinical pattern * no abnormal test results to account for vomiting (see exclusion criteria) Exclusion Criteria: * abnormal UGI with small bowel follow-through revealing an anatomic anomaly, inflammatory or obstructive * Significantly abnormal endoscopic biopsies (moderate to severe esophagitis, H. pylori) * Abnormal abdominal ultrasound revealing hydronephrosis, cholelithiasis, pancreatitis * Positive screening for endocrine disorder (diabetic ketoacidosis, Addison's) * Positive screening for inborn errors of metabolism (hypoglycemia, lactic acidosis, hyperammonemia, organic acidemia, amino aciduria, elevated beta-ALA, porphobilinogen)

What they're measuring

How two vitamin supplements are being used to treat cyclic vomiting syndrome

Timeframe: Two years

Trial details

NCT IDNCT00728104

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-01

View on ClinicalTrials.gov More Cyclic Vomiting Syndrome trials