Evaluate Efficacy, Safety & Subject Satisfaction of Pain Management With Pliaglis® Cream for Dermal Filler Injections

Inclusion Criteria: * Male or Female Subjects 30 - 65 years of age * Subject undergoing cosmetic dermal filler injections for correction of nasolabial folds. Treatment sites should be comparable, requiring the same number of injections on each nasolabial fold * Subjects diagnosed with moderate nasolabial folds (Wrinkle Severity Rating Scale of grade 3) Exclusion Criteria: * Subjects under treatment for a dermatologic condition on the face, which may interfere with the safe evaluation of the study treatment (e.g. eczema, psoriasis, severe sun-damage, dermatitis), have damaged, denuded or broken skin at the designated treatment site and/or have scarring or infection of the area to be treated * Subjects who have taken prescription or non-prescription analgesic medication during the 24 hour period prior to the procedure * Subjects with a history of bleeding or clotting disorders * Subjects who have used ASA (aspirin), NSAIDs (Non-Steroidal Anti- inflammatory Drugs), anticoagulants, St. John's Wort or high doses of Vitamin E (above the recommended daily allowance) within 2 weeks prior to the procedure