CompletedNot Applicable

Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia

United States8 participantsStarted 2006-04-26

Plain-language summary

The purpose of this research study is to see if a specific protein that we are interested in is involved in scarring hair loss. If these proteins are involved, further genetic work may also better define the disease as well as future treatment options.

Who can participate

Age range

30 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants ages 30 years or older with a biopsy- proven diagnosis of CCSA. * Undergone standard of care treatment for CCSA by a WFUSM Dermatologist * Women of child bearing age will be required to have a negative pregnancy test in order to participate in the study * Participants ages 30 years or older with a biopsy- proven diagnosis of LP. * Participants ages 30 years or older with a biopsy- proven diagnosis of DLE. * Healthy participants must be ages 30 years or older. Exclusion Criteria: * Age less than 30 years of age. * Clinically evident bacterial or viral infection of the scalp. * Pregnant or nursing woman of child-bearing potential. * Participation in any other investigative research study involving study medication. * Inability to return for the biopsy visit.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

To evaluate the expression of Fas protein in skin biopsies of participants with central centrifugal scarring alopecia (CCSA), lichen planopilaris (LP) and discoid lupus erythematosus (DLE) and in healthy controls.

Timeframe: 8 weeks

Trial details

NCT IDNCT00691769

SponsorWake Forest University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-11-26

View on ClinicalTrials.gov More Central Centrifugal Scarring Alopecia trials