TerminatedNot Applicable

Nitrofurantoin and Urinary Tract Infections (UTIs)

Stopped: Inadequate patient recruitment

United States10 participantsStarted 2008-05

Plain-language summary

Urinary tract infection (UTI) is the most common complication after surgery for prolapse or urinary incontinence. UTIs are painful and have the potential to turn into kidney infections. We are asking women who self-catheterize after surgery to try either an antibiotic or a placebo pill so we can see if we can prevent UTIs without causing side effects. This study will not require any additional visits or blood draws. You will be asked to answer some questions, keep a brief diary of your experience, and immediately report any symptoms of a UTI to your doctor.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women who fail a post-operative voiding trial and are willing to learn clean intermittent self-catheterization (CISC) prior to discharge from the hospital Exclusion Criteria: * Known drug allergy to nitrofurantoin * A history of renal insufficiency * Renal transplant * Renal nephropathy * A recent history of more than 3 Urinary Tract Infections (UTIs) per year * Known immunocompromised condition (organ transplant, chemotherapy for cancer or arthritis, autoimmune diseases (lupus etc)).

What they're measuring

Frequency of Symptomatic UTI's Confirmed With a Positive Urine Culture Within 6 to 8 Weeks After CISC Teaching and Implementation

Timeframe: 6 to 8 weeks after surgery

Trial details

NCT IDNCT00678041

SponsorUniversity of Pittsburgh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2009-05

Results submitted2016-05-10

View on ClinicalTrials.gov More Urinary Tract Infections trials