TerminatedPhase 3

Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the Early Menopause

Germany126 participantsStarted 2008-04

Plain-language summary

The aim of the study is to compare the effect of a progressive, periodized exercise training designed to impact bone, CHD-risk-factors and menopausal complaints versus the combined effect of exercise and "phytoestrogen" (cimicifuga racemosa; CR). After randomization, 84 females 1-3 year postmenopausal with no medication or illness affecting bone metabolism exercise over 12 months (EG; 42 with, 42 without CR), 42 women serve as wellness-control. Three group training sessions/week will be performed in the EG. Both groups will be individually supplemented with calcium and Vit-D (cholecalciferol).

Who can participate

Age range45 Years – 55 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 1-3 years early postmenopausal * Caucasian race Exclusion Criteria: * CHD-diseases * thrombosis, embolism * fractures at lumbar spine or hip * secondary osteoporosis * hyperparathyroidism * medication, diseases with impact on muscle or bone * cancer and hormone derived malign diseases * weight reduction of \> 5 kg during the last 6 months

What they're measuring

Bone Mineral Density

Timeframe: baseline, 12 month

Trial details

NCT IDNCT00663104

SponsorUniversity of Erlangen-Nürnberg Medical School

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2009-06

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