CompletedPhase 4

Comparison of Acceleromyography (AMG) and Mechanomyography (MMG) for Establishing Potency of Neuromuscular Blocking Agents

Denmark40 participantsStarted 2007-12

Plain-language summary

The purpose of this study was to compare two methods for neuromuscular monitoring, acceleromyography and mechanomyography for establishing the dose-response relationship and the potency of a neuromuscular blocking agent using rocuronium as an example. We hypothesized that there would be no significant difference between potencies estimated using acceleromyography and mechanomyography.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ASA I-III * Ideal weight +/-20% * Both arms available for neuromuscular monitoring * Surgery in supine position * Participated surgery time more than 30 min Exclusion Criteria: * Pregnant and breast-feeding women * Patients with known illness or use of medications known to influence the neuromuscular transmission * Known significant renal or hepatic dysfunction * Allergy to medications used in the study

What they're measuring

Comparison of ED50 with the two methods

Trial details

NCT IDNCT00660413

SponsorRigshospitalet, Denmark

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2008-02

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