Efficacy of Nicotine Acid on Dyslipidaemia in Patients With Metabolic Syndrome

Inclusion Criteria: * dyslipidemia (triglycerides \>= 150 mg/dl and/or decreased levels of HDL-cholesterol \<40 mg/dl in men or \< 50 mg/dl in women) * further components of the metabolic syndrome: Hypertension: blood pressure \>= 130/85 mmHg or/and Hyperglycemia: fasting plasma glucose \>= 100 mg/dl or/and 2 hour plasma glucose after 75g glucose load (OGTT) \>= 140 mg/dl or/and Obesity: waist circumferences \> 102 cm in men or \>88 cm in women Exclusion Criteria: * Contraindication and incompatibility of nicotine acid * Patients with ulcus ventriculi or ulcus duodeni * Intake of lipid lowering drugs \< 6 weeks before randomization * therapy of type 2 diabetes with insulin, glitazones, acarbose or more than one antidiabetic drug (only mono-therapy with metformin or sulfonyl urea is permit) - no acceptable therapy of diabetes with levels of HbA1C\>=8.0% * cardiovascular events in the last 6 months * chronic inflammatory diseases (lupus erythematodes, arthritis, morbus Crohn or colitis ulcerosa) * ALAT elevation 2.5 times more than the normal limit * pregnancy