CompletedNot Applicable

Examining the Long-Term Risks of Oophorectomy

United States32,175 participantsStarted 1980-01

Plain-language summary

At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.

Who can participate

Age range30 Years – 55 Years

SexFEMALE

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Inclusion Criteria: * Women who had hysterectomies were classified into simple hysterectomy or hysterectomy with both ovaries removed. Exclusion Criteria: * Evidence of cancer, coronary heart disease (MI or Angina Pectoris), stroke, or hip fracture before entering the study were excluded. Cancer as an indication for hysterectomy also excluded. * Women reporting unilateral oophorectomy, unknown oophorectomy status, unknown age of hysterectomy, or those who had oophorectomy before hysterectomy were excluded.

What they're measuring

mortality and morbidity due to the following conditions: coronary heart disease, stroke, breast cancer, ovarian cancer, other cancer, hip fracture and death from all causes.

Timeframe: 28 years

Trial details

NCT IDNCT00655447

SponsorParker, William H., M.D.

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2004-06

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