CompletedPhase 3

Progression of Carotid Artery Atheroma in Moderately Hypercholesterolemic Subjects

200 participantsStarted 2000-01

Plain-language summary

The purpose of this study is to examine the changes in the carotid artery when subjects receive high or low doses of rosuvastatin.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Fasting blood low density lipoprotein cholesterol level as defined by the protocol * Diagnosed carotid arterial stenosis Exclusion Criteria: * The use of lipid lowering drugs or dietary supplements after Visit 1. * Heavy or total occlusion of the carotid artery or recent stroke * Uncontrolled hypertension, hypothyroidism, alcohol or drug abuse

What they're measuring

Changes in carotid wall volume as measured by MRI scan

Timeframe: At 40 weeks and 104 weeks

Trial details

NCT IDNCT00654394

SponsorAstraZeneca

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

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