Comparison of Best Medical Treatment Versus Best Medical Treatment Plus Renal Artery Stenting

Inclusion Criteria: * Age ≥ 18 years * Informed consent signed by patient (and/or legal guardian), * Hemodynamically relevant de novo unilateral or bilateral atherosclerotic renal artery diameter stenosis RAS (≥ 70%) * Estimated GFR \> 10 ml/min calculated using the abbreviated Modification of Diet in Renal Disease (MDRD) Study equation, * Patients presenting mild, moderate or severe hypertension (defined according to the WHO guidelines) and/or renal dysfunction, * Target lesion must be completely coverable by one study stent, * Total target lesion length estimated to be less than 19 mm, * Target lesion accessible to direct stenting or, after pre-dilation, is likely to sufficiently benefit from stenting (at the discretion of the investigator), * Renal reference vessel diameter (RVD) of ≥ 4.0 mm and \< 7.0 mm based on visual estimation, * Willingness to comply with all the specified follow-up evaluations. Exclusion Criteria: * Estimated GFR ≤ 10 ml/min, * Renal atrophy or kidney length \< 7cm (referring to kidney with target lesion), * Patient not eligible for PTRAS, * Patient not eligible for stenting, * Target lesion occlusion, * Target lesion and/or target vessel proximal to the target lesion is severely calcified, * Treatment of branch lesion required, * Fresh thrombus or embolic lesion * Need for embolic protection in previous or planned PTRAS, * Clotting disorders, * INR \> 2.5 before the intervention, * Patient presents fibromuscular dysplasia, * Prior revascularizat…