CompletedPhase 4

Effects of Hydration to Prevent Contrast Induced Nephropathy in PCI for ST-elevation Myocardial Infarction.

Italy599 participantsStarted 2007-06

Plain-language summary

The aim of the study is to test the efficacy of low versus high volume hydration and two different solutions (sodium chloride versus sodium bicarbonate) in preventing contrast induced nephropathy (CIN) in ST elevation myocardial infarction (STEMI) patients undergoing primary PCI.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \> 18 years of years * Chest pain lasting at least 30 minutes, non responsive to nitrates, associated to ST elevation of at least 0.2 mV on surface ECG in two or more contiguous leads or to new left bundle branch block. * Informed consent Exclusion Criteria: * Chronic hemodialytic or peritoneal treatment * Coronary anatomy unsuitable for PCI * Need of emergency coronary artery by-pass grafting * Post-anoxic coma * Pregnancy

What they're measuring

contrast induced nephropathy incidence

Timeframe: 24, 48 and 72 hours

Trial details

NCT IDNCT00639912

SponsorAzienda USL Reggio Emilia - IRCCS

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2010-05

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