CompletedPhase 4

The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome

Australia40 participantsStarted 2008-02

Plain-language summary

We hypothesise that fish oils will have a beneficial effect on cardiometabolic parameters in women with PCOS. The purpose of this study therefore is to examine the effects of fish oils on blood pressure, heart rate variability and liver fat content in obese women with the polycystic ovary syndrome.

Who can participate

Age range18 Years – 50 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Overweight/obese women with PCOS as per 1990 NIH criteria (see below) * Non-smokers * Age\>18 years, premenopausal * Acceptable to have/be on treatment for type 2 diabetes mellitus and/or dyslipidaemia * Acceptable to be taking the oral contraceptive pill Exclusion Criteria: * Uncontrolled hypertension (BP\>160/100mmHg) * Known co-morbidities including liver or renal disease * Already taking fish oil supplements * Other intercurrent illness (major surgery, CV event) * Smokers * Alcohol intake \>20g/day * Pregnancy * Any metallic implant (contraindication for MRI).

What they're measuring

24 hour ambulatory systolic blood pressure

Timeframe: week 8 and week 24

Trial details

NCT IDNCT00620529

SponsorKeogh Institute for Medical Research

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2008-12

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