TerminatedPhase 4

Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy

Stopped: Study terminated due to low enrollment

United States22 participantsStarted 2008-02

Plain-language summary

The purpose of the study is to determine whether the combination of the the three drugs gabapentin, duloxetine, and donepezil are effective in treating pain in people with diabetic neuropathy or patients with failed low back syndrome (chronic back pain).

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of diabetic neuropathy * Age 18-80 * Willing to temporarily discontinue gabapentin or monoamine reuptake inhibitors upon entry into the study Exclusion Criteria: * Pregnancy * Allergy to study medications * Uncontrolled narrow-angle glaucoma * Currently being treatment with thioridazine (Mellaril) * Unstable medical conditions including cardiac, pulmonary, renal or hepatic diseases * Treatment with a monoamine oxidase inhibitor (MAOI) within 14 days of randomization

What they're measuring

Visual Analog Scale for Pain

Timeframe: Study completion (16 weeks)

Trial details

NCT IDNCT00619983

SponsorWake Forest University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-05

Results submitted2017-07-11

View on ClinicalTrials.gov More Diabetic Neuropathic Pain trials