CompletedPhase 4

Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic Women

United States20 participantsStarted 2008-01

Plain-language summary

This study will enroll 20 adult Hispanic women. Participants will apply 4% hydroquinone cream twice daily to affected areas on the face for 14 weeks and half the face will be peeled with 20-30% salicylic acid every two weeks for a total of 4 peels. The first two peels will be 20% salicylic acid and the second two peels will be with 30% salicylic acid. The purpose of the study will be to evaluate the safety and efficacy of salicylic acid combined with 4% hydroquinone versus 4% hydroquinone alone.

Who can participate

Age range18 Years – 65 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Hispanic women ages 18-65 years of age with moderate to severe melasma * English and Spanish-speaking women Exclusion Criteria: * Pregnant or breast-feeding women * Subjects who have used 4% hydroquinone within 3 months of study start * Subjects who have used chemical peels, microdermabrasion or facial laser treatments within 9 months of study start

What they're measuring

Number of Participants Showing Improvement of Melasma Based on Mexameter Readings

Timeframe: 14 weeks

Trial details

NCT IDNCT00616239

SponsorUniversity of Texas Southwestern Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-03

Results submitted2013-08-26

View on ClinicalTrials.gov More Melasma trials