CompletedPhase 4

(Gastrografin Use in Small Bowel Obstruction Caused by Adherences)

Italy76 participantsStarted 2003-09

Plain-language summary

Adhesive small intestine obstruction (ASIO) is an important cause of hospital admission and a very common disease. Any improvement in this field will benefit many patients by reducing the operative rate. Patients with this disease are difficult to evaluate and to manage and their treatment is controversial. Emergency surgery is mandatory when strangulation is suspected or in the case of total obstruction. On the other hand, conservative non-operative treatment is indicated in the case of partial obstruction. The role of water-soluble contrast medium (Gastrografin®: GG) in ASIO is still debated with regard to the therapeutic value. The aim of our study was to determine the therapeutic role of Gastrografin in patients with small intestine obstruction without strangulation caused by adherences (ASIO).

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients (\>18 years) * History of previous abdominal surgical procedures * Clinical and radiological evidence of adhesive small intestine obstruction without signs of strangulation and peritonism * ASA I-III patients * Informed consent Exclusion Criteria: * Suspicion of strangulation * Actual presence or high suspicion of intra-abdominal malignancy * Suspicion or history of peritoneal carcinomatosis * active inflammatory bowel disease * Positive history of radiotherapy on the abdominal region * Obstructed hernias

What they're measuring

The operative rate in ASIO patients

Timeframe: Within 72 hours and during hospital stay

Trial details

NCT IDNCT00601809

SponsorUniversity of Bologna

Sponsor typeOTHER

Study typeINTERVENTIONAL

View on ClinicalTrials.gov More Adhesive Small Intestine Obstruction trials