CompletedNot Applicable

Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome

United States1,247 participantsStarted 2005-03

Plain-language summary

Pleuropulmonary Blastoma (PPB) is a rare lung tumor which develops in childhood. The underlying genetic factors which contribute to the development and progression of PPB are not defined. We are working to identify the genetic factors which may contribute to the development of this rare tumor.

Who can participate

Age range1 Day – 95 Years

SexALL

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Inclusion Criteria: * Child or adult diagnosed with pleuropulmonary blastoma, cystic nephroma, embryonal rhabdomyosarcoma of uterine cervix, ovarian Sertoli-Leydig tumor or gynandroblastoma, pineoblastoma, pituitary blastoma, nasal chondromesenchymal hamartoma, medulloepithelioma, Wilms tumor, germline or mosaic DICER1 mutation Exclusion Criteria: * child or adult who does not fit inclusion criteria as listed above

What they're measuring

Identify the genetic factors which contribute to the development or progression of pleuropulmonary blastoma

Timeframe: 10 years

Trial details

NCT IDNCT00565903

SponsorAshley Hill

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-12-31

View on ClinicalTrials.gov More Pleuropulmonary Blastoma trials