CompletedPhase 4

Pain Post Abdominal Laparoscopy Prevention With Arcoxia

60 participantsStarted 2006-04

Plain-language summary

To test the analgesic efficacy of etoricoxib used before a surgical procedure compared to the already known effect when administered after such a procedure. Patient will be receiving either etoricoxib or the respective placebo one hour before surgery, then two hours after those receiving the active will receive placebo and those that received placebo will be given etoricoxib. Pain score measurements will be performed sequentially. Rescue medication will be available all the time.

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Voluntary acceptance to participate in the study and signed the informed consent form * Age older than 18 years old and younger than 70 years * Diagnosis of appendicitis, cholecystitis or ovarian cysts suitable of laparoscopic surgery Exclusion Criteria: * Age less than 18 years or older than 70 years. * Laparoscopic procedures for diagnostic purposes. * Current use of anticoagulants. * Known hypersensitivity to etoricoxib or its components. * History of a CABG or MI (less than 1 year) * History of unstable angina (over the past six months). * Current inflammatory bowel disease. * Uncontrolled hypertension or heart failure * Renal dysfunction/impairment (creatinine clearance \< 30ml/min) * Cirrhosis or severe hepatic dysfunction * Any degree of dehydration (mild to severe)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

To measure the amount of rescue medication (opioid) needed to relief

Timeframe: Every hour after surgery

Trial details

NCT IDNCT00565682

SponsorHospital Vozandez

Sponsor typeOTHER

Study typeINTERVENTIONAL

View on ClinicalTrials.gov More Laparoscopic Surgery for Appendicitis trials