TerminatedNot Applicable

Effect of Nortriptyline on Abdominal Pain/Discomfort and Quality of Life in Patients With Nonulcer Dyspepsia

Stopped: Not enough participants - only 5 since the study started

United States5 participantsStarted 2008-02

Plain-language summary

The purpose of this study is to determine if use of Nortriptyline will improve symptoms and quality of life in patients who have nonulcer dyspepsia.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Men and Women * Ages 18-65 * Meet Rome III criteria for functional dyspepsia * Endoscopy within 1 year Exclusion Criteria: * Allergic reaction or history of adverse events with Nortriptyline or tricyclic antidepressants * Organic cause found on physical examination * Organic cause found on lab work: Complete Blood Count, Comprehensive Metabolic Panel, Thyroid stimulating hormone, Tissue transglutaminase Immunoglobulin A * Predominantly Gastroesophageal reflux symptoms * Current Helicobacter pylori infection * History of Peptic ulcer disease * Non steroidal antiinflammatory use use \> 2x/wk * Pregnant or planning pregnancy * History of major depression * Abdominal surgery in the last year

What they're measuring

Question on Whether Patient Has Had Adequate Relief of Abdominal Pain or Discomfort Reported by a Simple Yes or no Answer.

Timeframe: 8 weeks

Trial details

NCT IDNCT00547703

SponsorThe Cleveland Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2010-04

Results submitted2012-02-20

View on ClinicalTrials.gov More Non Ulcer Dyspepsia trials