TerminatedNot Applicable

Effect of Serotonin Level on Constipation Caused by Chemotherapy in Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Stopped: Funding unavailable

United States13 participantsStarted 2007-04

Plain-language summary

RATIONALE: Gathering information about changes in serotonin levels in patients undergoing chemotherapy for ovarian cancer, fallopian tube cancer, or primary peritoneal cancer may help doctors learn more about constipation caused by chemotherapy. PURPOSE: This clinical trial is studying how blood levels of serotonin effect constipation caused by chemotherapy in patients with newly diagnosed ovarian cancer, fallopian tube cancer, or primary peritoneal cancer.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Newly diagnosed ovarian, fallopian tube, or primary peritoneal cancer * Planned to undergo 6 courses of a taxane and platinum-containing regimen Exclusion Criteria: * Ovarian low malignant potential tumor * History of constipation or irritable bowel syndrome * History of colorectal cancer * Prior bowel resection at time of staging/cytoreductive surgery * Prior abdominal-pelvic radiation * Prior bowel surgery

What they're measuring

Alterations in serotonin levels associated with increased constipation

Timeframe: PreDose, Post 3rd Cycle, Post Treatment and 4 Months Post Treatment

Trial details

NCT IDNCT00536523

SponsorUniversity of Minnesota

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2009-12

View on ClinicalTrials.gov More Constipation trials