Hantavirus Transmission in Households in Chile (NCT00533767) | Clinical Trial Compass
TerminatedNot Applicable
Hantavirus Transmission in Households in Chile
Stopped: This is not a clinical trial and was inadvertently added to the system.
Chile197 participantsStarted 2007-07
Plain-language summary
This study is designed to evaluate the transmission of hantavirus in Chile. It is an observational study that will look at close household contacts of people who have been diagnosed with hantavirus infections that result in a serious illness to see how frequently they become infected. Subjects who enroll in the study will donate samples of body fluids (e.g., blood, saliva, stool, urine, respiratory and vaginal secretions) to allow the researchers to see if hantavirus is present in those fluids and if so, how much. Subjects will also be interviewed to identify household conditions that may be associated with transmission. Up to 76 index cases (people who are first diagnosed with hantavirus cadiopulmonary illness) and up to 140 of their close contacts will be enrolled. Subjects will be followed for about 6 weeks.
Who can participate
Age range2 Years
SexALL
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Inclusion criteria
✓. Confirmed diagnosis, positive hantavirus IgM assay or detection of hantavirus in plasma or serum by RT-PCR.
✓. Signed informed consent form.
✓. Less than 96 hours have transpired since the diagnosis was confirmed.
✓. Any person, 2 years of age or older, who has been in close contact with the index case at any point from 30 days before to 7 days after the onset of symptoms in the index case.
✓. Close contact must include: sexual contact and/or deep kissing and/or slept in same bed and/or provided direct care to index case.
Exclusion criteria
✕. Index case does not have or agree to give the names of his/her close contacts.
✕. Not a suitable candidate in the opinion of the investigator.
✕. Confirmed current or previous infection with Andes virus.
✕. Younger than 2 years of age.
What they're measuring
1
Estimate the secondary attack rate among close household contacts of index cases with hantavirus cardiopulmonary syndrome in Chile