Treatment of Cutaneous Lupus Erythematosus (CLE) With the 595 nm Flashlamp Pulsed Dye Laser

Inclusion Criteria: * Cutaneous lupus erythematosus confirmed by histological analysis * Fitzpatrick I-III skin type (very fair, fair, or medium skin) * Stable disease and in relatively good health * Presence of two skin lesions that are suitable for laser treatment * Written informed consent available prior to any screening procedures * Female patients must be willing to use the appropriate birth control measures that will prevent pregnancy from the time of signing informed consent through 60 days after their last laser treatment Exclusion Criteria: * Clinically significant dyspigmentation * History of isotretinoin use, phenol peels, filler injections (collagen, fat), dermabrasion within the past 3 years * History of hypertrophic scarring * History of photosensitivity in the 585-600 nm wavelength region * History of seizure disorders triggered by light * Pregnancy and lactation * Fitzpatrick V or VI skin type (moderately pigmented brown, or markedly pigmented black skin) * Patients receiving anticoagulants and/or medication for which sunlight exposure is a contraindication * Known malignancy or prior malignancy, other than non-melanoma skin cancer