RecruitingNot Applicable

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

United States500 participantsStarted 2007-01-15

Plain-language summary

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the next. In this study, we are collecting genetic material and medical information to try to determine if genetic factors play a role in CP/CPPS. We will be collecting DNA (from Blood/Saliva sample) and urine from each participant. Bladder tissue from affected individuals will also be collected. Individuals and families with CP/CPPS will be enrolled. Family members of an individual with CP/CPPS are eligible whether or not they also experience CP/CPPS symptoms.

Who can participate

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Have symptoms for at least 3 months within the preceding 6 months: * Pain in the pelvic area * Urinary frequency and/or * Urinary urgency and/or * Sexual dysfunction (erectile dysfunction) * Have CP/CPPS, Interstitial Cystitis (IC), Bladder Pain Syndrome BPS, or Bladder Fasciculation Syndrome (BFS) * Be willing to provide a blood/saliva, bladder tissue (from previous biopsy) and urine sample * Agree to complete several brief questionnaires * Family member of someone with CP/CPPS, BPS, IC or BFS * Live in the USA or Canada Exclusion Criteria: * Major structural/anatomical urinary tract abnormalities * Underlying inborn or congenital conditions which affect the urinary tract * Surgery/chemotherapy in the pelvic area * Bacterial cause to CP/CPPS or recurrent Urinary tract infections (UTI) * Traumatic cause to CP/CPPS

Trial details

NCT IDNCT00499317

SponsorBoston Children's Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12-31

Contact for this trial

Elicia Estrella, MS, LCGC

617-919-4552 elicia.estrella@childrens.harvard.edu

View on ClinicalTrials.gov More Chronic Prostatitis (CP) trials

Plain-language summary

Who can participate

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.