Anisometropia Amblyopia Improved by Perceptual Learning and Patching (NCT00498641) | Clinical Trial Compass
CompletedPhase 3
Anisometropia Amblyopia Improved by Perceptual Learning and Patching
Started 2005-01
Plain-language summary
To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.
Who can participate
Age range
3 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Anisometropia without strabismus
* An interocular acuity difference of at least 0.2 logMAR in children (3-7 years of age) or in older children and adult patients without a history of patching or atropine penalization
* All patients wore their spectacle at least one year
Exclusion Criteria:
* A history of prior spectacle correction
* A history of patching or optical penalization
* The existence of an ocular disease that could contribute to decreased visual acuity
* Learning difficulties
* The presence of strabismus
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compared perceptual learning with patching for anisometropic amblyopia — since it's already completed, can you tell me what the results showed about which approach improved vision more, and whether those results might apply to my situation?
2The trial measured both logMAR visual acuity and contrast sensitivity — does my current level of amblyopia affect which of those outcomes matters most for my day-to-day vision, and should I be tracking both?
3Since this was a Phase 3 trial that has finished, is perceptual learning now considered a proven or standard alternative to patching, or is patching still the recommended first step for someone with my type of anisometropic amblyopia?
4Perceptual learning involves visual training exercises rather than just wearing a patch — realistically, how demanding is that kind of treatment in terms of time and effort, and would that be manageable given my daily routine?
5Are there any factors about my specific prescription difference between my two eyes that would make me a better candidate for one treatment approach over the other based on what this trial found?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Corrected amblyopic logMAR visual acuity and contrast sensitivity function