CompletedNot Applicable

Local Collagen-Gentamicin and Extra Fixation of the Sternum for Prevention of Sternal Wound Infection in Cardiac Surgery

Sweden1,358 participantsStarted 2007-01

Plain-language summary

The aim of the present study is to evaluate a new technique for prevention of sternal wound infection consisting of local application of collagen-gentamicin in addition to routine i.v. antibiotic prophylaxis. The technique has been evaluated in a previous randomised study. The aim of the present study is to evaluate the technique after it has been introduced in clinical practise to monitor the bacterial antibiotic susceptibility and to verify that the suggested reduction in sternal wound infection still exits.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * All consecutive cardiac surgery patients operated via median sternotomy Exclusion Criteria: * Existing inclusion of the patient in another study of treatment aimed at reducing postoperative SWI. * Known allergy or other contraindication to gentamicin or bovine collagen. * Pregnancy or breast feeding * Treatment with aminoglycosides during the last week

What they're measuring

The incidences of methicillin- and gentamicin resistant microbiological agents in sternal wound infections that develop in study patients

Timeframe: Within 2 months postoperatively

Trial details

NCT IDNCT00484055

SponsorRegion Örebro County

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2008-08

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