Hyperproteic Nutrition:Correlation of BUN to Nitrogen Balance (NCT00480259) | Clinical Trial Compass
CompletedNot Applicable
Hyperproteic Nutrition:Correlation of BUN to Nitrogen Balance
8 participantsStarted 2007-06-01
Plain-language summary
This study is designed to determine if the following are true. When protein requirements exceed metabolic requirements, blood urea nitrogen(BUN) levels will rise. Elevated BUN levels in the absence of renal failure, hepatic failure, or GI bleeding, will be correlated with improved nitrogen balance and inversely correlated with infection rates, days of mechanical ventilation, ICU days, and total hospital days.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Greater then or equal to 18 years of age and patient in Intensive Care Unit
* Receiving enteral nutrition, with expected duration of at least 5 days
* Blood urea nitrogen and creatinine clearance are part of routine blood work
* Indwelling urinary catheter in place
Exclusion Criteria:
* Renal or hepatic failure
* Current or history(past 6 mos) of GI bleeding
* Serum creatinine on day of screening of equal to or greater then 1.5 mg/dl
* Creatinine Clearance on day of screening of equal to or less then 30ml/min
* Hypovolemia resulting in increased BUN
* Septic shock
* Blood urea nitrogen on day of screening equal to or greater then 30mg/dl
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Increase in BUN
Timeframe: Unable to document -incomplete information and investigator no longer at institution; no records available