TerminatedNot Applicable

Genetic Basis of Hemangiomas

United States300 participantsStarted 2007-04

Plain-language summary

The purpose of this study is to determine if there are genes that are common in children with infantile hemangioma. This information will allow physicians to improve care for patients who have been diagnosed with this disease and to provide their parents with more complete information regarding the cause of this disease. This research is being done because many unanswered questions remain regarding children with infantile hemangioma. There are very few medications to treat infants with hemangiomas.

Who can participate

SexALL

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Study Population Inclusion Criteria: * No limit to age * Diagnosis of infantile hemangioma and/or vascular anomaly * Unaffected twin sibling * Each patient's authorized legal guardian must understand the nature of the study and must provide written informed consent. Each patient must also give assent to study participation. Study Population Exclusion Criteria: * Diagnosis other than infantile hemangioma or vascular anomaly * If the lesion has resolved and cannot be confirmed as a hemangioma by clinical exam * If the biologic parents are unwilling or unable to submit DNA samples the child will be excluded from the DNA study. Therefore, if DNA samples cannot be or are not obtained from both biologic parents, the child and family will be excluded from the study.

What they're measuring

SNP

Timeframe: 3 years

Trial details

NCT IDNCT00466375

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2014-11

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