Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM

Inclusion Criteria: * Diagnosed with angiomyolipomas and have either Tuberous Sclerosis complex or Lymphangioleiomyomatosis * Between the gaes of 18 and 65 years * Competency to voluntarily consent * Clinically definite diagnosis of tuberous sclerosis or S-LAM * Adequate contraception * At least one angiomyolipoma of 1 cm or greater in largest diameter Exclusion Criteria: * Use of continuous supplemental oxygen * Concurrent infection * Recent surgery * Ongoing or planned pregnancy * Lactation * Use of an investigational drug within the last 30 days of study entrance