RATIONALE: Identifying gene mutations and other risk factors in patients with melanoma and in families with a history of hereditary melanoma may help doctors identify persons at risk for melanoma and other types of cancer. It may also help the study of cancer in the future. PURPOSE: This clinical trial is studying gene mutations in patients with melanoma and in families with a history of hereditary melanoma.
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Predictive significance of melanoma susceptibility gene (MSG) mutations in the CDKN2A gene
Susceptibility to other types of cancer as a feature of MSG mutations
Risk of other types of cancers in mutation carriers
Environmental exposures, in particular sun exposure, that modify risk of melanoma in MSG mutation carriers