Study of Families With Melanoma (NCT00445783) | Clinical Trial Compass
UnknownNot Applicable
Study of Families With Melanoma
United Kingdom3,700 participantsStarted 2000-07
Plain-language summary
RATIONALE: A study that evaluates patients' lifestyle, skin, and blood and tissue samples may help doctors understand the risk factors for melanoma relapse.
PURPOSE: This clinical trial is studying the risk factors for melanoma in families with melanoma.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
DISEASE CHARACTERISTICS:
* Meets 1 of the following criteria:
* Newly diagnosed primary invasive melanoma (patient group)
* Lentigo maligna malignant melanoma allowed
* Rare variants of melanoma allowed, including any of the following:
* Acral lentiginous
* Subungual
* Ear, nose, and throat
* Oropharyngeal
* Perineal
* Vaginal
* Vulval
* Rectal
* Nodal with no known primary
* Patients undergoing sentinel node biopsy are eligible
* No in situ melanoma, melanocytic intraepidermal neoplasia, or ocular melanoma
* Healthy participant meeting either of the following criteria (control group):
* Relative of a patient who was diagnosed with melanoma after September 2005
* Healthy volunteer who is age- and sex-matched for patients who were diagnosed with melanoma before October 2005
PATIENT CHARACTERISTICS:
* Not specified
PRIOR CONCURRENT THERAPY:
* Not specified
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Lifestyle factors governing relapse from melanoma
2
Genes governing relapse from melanoma
3
Sun exposure and genes that cause melanoma
4
Unusual moles related to sun exposure and genes that cause melanoma
Trial details
NCT IDNCT00445783
SponsorLeeds Cancer Centre at St. James's University Hospital