Meningococcal B Vaccination in University Students

Inclusion Criteria: * Informed written consent given for four immunisations (group 2 will receive 3 doses only) with MeNZB TM vaccine, as well as for eight blood draws to be taken as described in the patient information leaflet in appendix 2 * Healthy adults (university students) aged 18 up to 40 years on inclusion in the study Exclusion Criteria: On enrolment: * Previous history of bacteriologically confirmed disease caused by N. meningitidis * Prior receipt of any group B meningococcal vaccine * have had household contact with and/or intimate exposure to an individual with culture or PCR proven N. meningitidis serogroup B within the previous 60 days * have either received, or for whom there is intent to immunize with, any vaccines or investigational agents within 50 days prior to enrolment, through to 50 days following the last study vaccine administration, with the exception of influenza vaccines or post-exposure tetanus vaccination * have a history of any anaphylactic shock, urticaria or other allergic reaction after previous vaccinations or hypersensitivity to any vaccine component * have experienced significant acute or chronic infections requiring systemic antibiotic treatment within the past 14 days * have any present or suspected serious acute or chronic disease such as: cardiac or autoimmune disease, insulin dependent diabetes or progressive neurological disease or severe malnutrition, acute or progressive hepatic disease, acute or progressive renal disease; leu…