WithdrawnNot Applicable

Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer

Stopped: No patient enrollment occurred.

0Started 2003-12

Plain-language summary

RATIONALE: The use of a nicotine inhaler may help decrease appetite and relieve "hunger pain" (an intense craving for food) in patients with malignant bowel obstruction caused by cancer. PURPOSE: This randomized clinical trial is studying the side effects and how well a nicotine inhaler works in treating "hunger pain" in patients with malignant bowel obstruction caused by cancer.

Who can participate

Age range18 Years – 120 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Diagnosis of any incurable malignancy * Presence of malignant bowel obstruction * Must be on strict "nothing per os" (NPO) status over the next 48 hours * Ice chips allowed * Acknowledges that "hunger pain" is a problem PATIENT CHARACTERISTICS: * Mentally competent * No history of life-threatening arrhythmia * No severe or worsening angina * No accelerated hypertension * No known hypersensitivity to nicotine * Not pregnant or nursing * Negative pregnancy test PRIOR CONCURRENT THERAPY: * Concurrent short-term use of dexamethasone or other hormonal therapy or symptom control strategy allowed

What they're measuring

Determination of whether ≥ 50% of patients utilize nicotine for treating "hunger pain" ≥ 2 times over a 48-hour period

Timeframe: 48 Hours

Trial details

NCT IDNCT00425906

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

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