CompletedPhase 4

Dressing: Frequency of Change and Evaluation of an Antiseptic-Impregnated Catheter Dressing in ICU Patients

France1,600 participantsStarted 2007-01

Plain-language summary

The purpose of this study is to determine whether a catheter dressing every 7th day is not inferior to a catheter dressing every 3 days and if Chlorhexidine impregnated sponges are effective in preventing catheter-related infections in ICUs.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients older than 18 years * with at least a central venous catheter or an arterial catheter * whatever the first or subsequent CVC in a same patient * in any site of insertion (sub-clavian, jugular or femoral) * whatever le CVC is tunnelled or not * CVC inserted in the study ICU or immediately before by the intensisvist in the emergency unit or in the operative room, * CVC inserted under maximal barrier precautions Exclusion Criteria: * pulmonary artery catheter, haemodialysis/haemodiafiltration CVCs * known allergy to chlorhexidine * CVC not inserted under maximal barrier precautions * Expected duration of CVC for less than 48 hours * CVC inserted under emergency conditions

What they're measuring

Systemic catheter related sepsis as defined by a blinded expert panels to unmask differences between Chlorhexidine dressings and no Chlorhexidine dressings

Timeframe: 48 hours

Significant catheter culture >=103 cfu/ml for non inferiority between 7 days and 3 day catheter-dressing frequencies

Timeframe: 48 hours

Trial details

NCT IDNCT00417235

SponsorUniversity Hospital, Grenoble

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2008-06

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