CompletedPhase 2

Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Hodgkin's Lymphoma

648 participantsStarted 2002-11

Plain-language summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells. PURPOSE: This phase II trial is studying the side effects and how well giving combination chemotherapy together with radiation therapy works in treating young patients with Hodgkin's lymphoma.

Who can participate

Age range17 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Diagnosis of classic Hodgkin's lymphoma (HL) * Intermediate or advanced disease, including the following stages: * Stage I * Stage IIA, IIB, IIE, or IIBE * Stage IIIA or IIIBE * Stage IV PATIENT CHARACTERISTICS: * No other concurrent malignancies * No severe concurrent diseases (e.g., immune deficiency syndrome) PRIOR CONCURRENT THERAPY: * No prior chemotherapy or radiotherapy * Pre-phase therapy for large mediastinal tumor allowed

What they're measuring

Safety and efficacy

Reduction of gonadotoxicity

Quality assurance

Trial details

NCT IDNCT00416832

SponsorChristine Mauz-Körholz

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2005-12

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