CompletedNot Applicable

Side Effects of High-Dose Intensity-Modulated Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

20 participantsStarted 2004-06

Plain-language summary

RATIONALE: Tests that measure how much saliva is made, hearing, swallowing, voice function, and quality of life may improve the ability to plan treatment for patients with advanced head and neck cancer and may help doctors find better ways to treat the cancer. PURPOSE: This clinical trial is studying the side effects of high-dose intensity-modulated radiation therapy in treating patients with advanced head and neck cancer.

Who can participate

Age range18 Years – 120 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Histologically confirmed advanced head and neck cancer * Indication for radiotherapy or chemoradiotherapy as primary or postoperative therapy AND meets 1 of the following criteria: * More than 75% of bilateral parotid glands expected to receive ≥ 45 cGy of radiation using conventional treatment field design * Either or both central auditory apparatus predicted to receive \> 45 cGy of radiation PATIENT CHARACTERISTICS: * No comorbid medical condition that would preclude radiotherapy * No serious concurrent psychosocial, familial, sociological, geographical, or other condition that would preclude study compliance PRIOR CONCURRENT THERAPY: * See Disease Characteristics

What they're measuring

Stimulated saliva production at 6 months after completion of intensity-modulated radiotherapy (IMRT)

Comparison of salivary function of patients in current study to salivary function of historical controls

Trial details

NCT IDNCT00415025

SponsorUniversity of Wisconsin, Madison

Sponsor typeOTHER

Study typeOBSERVATIONAL

View on ClinicalTrials.gov More Head and Neck Cancer trials