LEO19123 Cream in the Treatment of Hand Eczema

Inclusion Criteria: * Clinical diagnosis of hand eczema with or without atopic etiology/background * Investigator.s Global Assessment of disease severity graded as at least mild at Visit 1 * Patients should be Caucasian males aged from 18 years * Attending a hospital outpatient clinic or the private practise of a dermatologist. * Following verbal and written information about the trial, the patient must provide signed and dated informed consent before any trial related activity is carried out, including activities relating to wash-out periods. Exclusion Criteria: * Systemic treatment with immunosuppressive drugs (e.g. methotrexate, cyclosporine, azathioprine) or corticosteroids within 4 weeks prior to randomisation. (Inhaled or intranasal steroids for asthma or rhinitis may be used). * PUVA or UVB therapy on the hands within 4 weeks prior to randomisation. * Topical treatment with immunomodulators (pimecrolimus, tacrolimus) or corticosteroids from WHO groups III or IV on the hands within 2 weeks prior to randomisation. * Other topical therapy on the hands (except for the use of emollient) within 1 week prior to randomisation. * Use of other treatment (drug, non-drug) on the hands during the trial except for the use of investigational product and emollient. * Concurrent skin diseases on the hands. * Current diagnosis of exfoliative dermatitis. * Significant clinical infection (impetiginised hand eczema) on the hands, which requires antibiotic treatment. * Known or suspected…