ProQuad® Intramuscular vs Subcutaneous

Inclusion Criteria: * Healthy participant of either gender, * Age 12 to 18 months, * Negative clinical history of measles, mumps, rubella, varicella and zoster, * Consent form signed by both holders of the parental authority or by the legal representative * Holder(s) of the the parental authority / legal representative able to understand the protocol requirements and to fill in the Diary Card. Exclusion Criteria: * Prior receipt of measles, mumps, rubella and/or varicella vaccine either alone or in any combination, * Any recent (≤30 days) exposure to measles, mumps, rubella, varicella and/or zoster * Any recent (≤3 days) history of febrile illness * Any severe chronic disease, * Active untreated tuberculosis, * Known personal history of seizure disorder, * Any known blood dyscrasias, leukemia, lymphomas of any type, or other malignant neoplasms affecting the haematopoietic and lymphatic systems, * Any severe thrombocytopenia or any other coagulation disorder that would contraindicate intramuscular injection, * Any immune impairment or humoral/cellular deficiency, neoplastic disease or depressed immunity including those resulting from corticosteroid \[any long-term (≥14 days) administration of systemic corticosteroid therapy given daily or on alternate days at high doses (≥2 mg/kg/day prednisone equivalent or ≥20 mg/day if weight more than 10 kg) within the previous 30 days\] or other immunosuppressive therapy, * Any previous (≤ 150 days) receipt of immune globulin or any b…